Faculty <br /> of Medicine
Faculty
of Medicine

Ms. Dehenak Gedara Pubudu Kalpani Senevirathna

Department of Biochemistry, Dehenak Gedara Pubudu Kalpani Senevirathna Lecturer (probationary) Phd. reading Bsc (Hons) in Molecular Biology and Biotechnology

Lecturer (probationary)

Bsc (Hons) in Molecular Biology and Biotechnology, Phd. reading
Email :kalpani.s@uwu.ac.lk

Positions Held

Faculty Representative: University Research & Higher Degrees Committee
Chair : Faculty Audio-Visual & Web Committee

  • Director, Examination Unit, Faculty of Medicine, Uva Wellassa University (July, 2024 -Present)
  • Chairperson, Audio – visual and web committee, Faculty of Medicine, Uva Wellassa University (December, 2024 -Present)
  • Faculty representative, University Research and Higher degrees committee, Uva Wellassa University (July, 2024 -Present)

Research Interest

  • Cancer biomarkers
  • Spectral Biomarkers
  • Molecular markers in disease diagnosis
  • Molecular Biology

Publications

Journal Publication

  1. Senevirathna, K., Mahakapuge, T.A.N., Jayawardana, N.U., Rajapakse, J., Gamage, C.U., Seneviratne, B., Perera, U., Kanmodi, K.K. and Jayasinghe, R., 2024. Diagnostic Potential of Salivary IL-1β, IL-8, SAT, S100P, and OAZ1 in Oral Squamous Cell Carcinoma, Oral Submucous Fibrosis, and Oral Lichen Planus Based on Findings from a Sri Lankan Cohort. Scientific Reports, 14:27226.
  2. Senevirathna, K., Mahakapuge, T.A.N., Jayawardana, N.U., Rajapakse, J., Gamage, C.U., Seneviratne, B., Perera, U., Kanmodi, K.K. and Jayasinghe, R., 2024. Serum mRNA levels of cytokeratin-19 and vascular endothelial growth factor in oral squamous cell carcinoma and oral potentially malignant disorders using RT-PCR. BMC Oral Health, 24(1), p.1062.
  3. Senevirathna, K., Mahakapuge, T.A.N., Ileperuma, P., Jayawardana, N.U., Jayarathne, L., Weerasekara, R., Gamage, C.U., Senevirathna, B., Perera, U., Jayasinghe, R. and Kanmodi, K.K., 2024. Correlation between serum heavy metals and the risk of oral squamous cell carcinoma and oral potentially malignant disorders. Scientific Reports, 14(1), p.19029.
  4. Jayawickrama, S. M., Ranaweera, P. M., Pradeep, R. G. G. R., Jayasinghe, Y. A., Senevirathna, K., Hilmi, A. J., … & Jayasinghe, R. D. (2024). Developments and future prospects of personalized medicine in head and neck squamous cell carcinoma diagnoses and treatments. Cancer Reports, 7(3), e2045.
  5. Senevirathna, K., Jayasinghe, Y.A., Jayawickrama, S.M., Amarasinghe, H. and Jayasinghe, R.D., 2023. Oral Cancer Disease among the Poor: A Sri Lankan Context. Oral, 3(3), pp.420-436.
  6. Senevirathna, K., Jayawickrama, S.M., Jayasinghe, Y.A., Prabani, K.I., Akshala, K., Pradeep, R.G., Damayanthi, H.D., Hettiarachchi, K., Dorji, T., Lucero‐Prisno, D.E. and Rajapakse, R.M., 2023. Nanoplatforms: The future of oral cancer treatment. Health Science Reports, 6(8), p.e1471.
  7. Senevirathna, K., Pradeep, R., Jayasinghe, Y.A., Jayawickrama, S.M., Illeperuma, R., Warnakulasuriya, S. and Jayasinghe, R.D., 2023. Carcinogenic Effects of Areca Nut and Its Metabolites: A Review of Experimental Evidence. Clinics and Practice, 13(2), pp.326-346.
  8. Senevirathna, K., Jayawardana, N., Gamage, C.U., Perera, U., Jayasinghe, R. and Seneviratne, B., 2023. Use of oral squamous cell carcinoma: A discussion paper. International Health Trends and Perspectives, 3(1), pp.1-15.
  9. Senevirathna, K., Hettiarachchi, K., Warnakulasuriya, S. and Jayasinghe, R., 2022. TikTok–Potential Impact on the Use of Smokeless Tobacco and Betel Quid by Young People. Asian Pacific Journal of Cancer Prevention, 23(11), pp.3665-3671.
  10. Senevirathna, K., Jayawardana, N.U., Chandrika, U.G., Jayasinghe, R.D., Perera, A.G.U. and Seneviratne, B., 2021. Metabolomics: a promising diagnostic tool for oral cavity cancer. Journal of Diagnostic Pathology, 16(2).
  11. Senevirathna, K., Jayawardana, N.U., Jayasinghe, R.D., Seneviratne, B. and Perera, A.U., 2021. Diagnostic Value of FTIR Spectroscopy, Metabolomic Screening and Molecular Genetics in Saliva for Early Detection of Oral Squamous Cell Carcinoma (OSCC). Medical & Clinical Research, 6 (2): 435-454.
  12. Senevirathna, D.G., Rathnayake, P.G., Ranaweera, L.T., Weebadde, C.K. and Sooriyapithirana, S.D., 2020. Assessment of the species delimits and seasonal variation of fruit size, organoleptic preference and phytochemical content of rose apple species in Sri Lanka. JTVA, 2(2), pp.13-38.

Abstract publications

  1. Y. Jayasinghe, P. Peiris, R. Pradeep, S. Jayawickrama, K. Senevirathna, N. Piyarathne, T. Ariyasena, N. Jayawardena, L. Jayasinghe, R. Weerasooriya, R. Jayasinghe. Comparison of toxic metals present in Sri Lankan areca nut varieties. World Dental Congress in Turkei September 2024, Istanbul, Türkiye, 12th to 15th September, 2024.
  2. Y. A. Jayasinghe, K. Sathkunaseelan, K. Senevirathna, K. Hettiarachchi, H. Amarasinghe, R. Jayasinghe. Public awareness on oral cancer and oral potentially malignant disorders in Central Province, Sri Lanka. World Dental Congress in Turkei September 2024, Istanbul, Türkiye, 12th to 15th September, 2024.
  3. K. Senevirathna, T.N. Mahakapuge, N. Jayawardana, R. P. V. J. Rajapakse, C. Udumalagala Gamage, B. Senevirathne, A.G. Unil Perera, R.D. Jayasinghe. Salivary Transcriptomic Diagnostics: Findings from a Study in Sri Lanka on Oral Squamous Cell Carcinoma, Oral Submucous Fibrosis, and Oral Lichen Planus. Proceedings of Peradeniya University International Research Sessions 2024, Sri Lanka, Vol. 25, 29th & 30th September 2024.
  4. K. Senevirathna, T.N. Mahakapuge, N. Jayawardana, R. P. V. J. Rajapakse, C. Udumalagala Gamage, B. Senevirathne, A.G. Unil Perera, R.D. Jayasinghe. Cytokeratin-19 and Vascular Endothelial Growth Factor (VEGF): Promising Biomarkers in the Detection of Oral Squamous Cell Carcinoma and Oral Potentially Malignant Disorders. Proceedings of Peradeniya University International Research Sessions 2024, Sri Lanka, Vol. 25, 29th & 30th September 2024.
  5. K. Senevirathna, T.N. Mahakapuge, N. Jayawardana, I.P.L. Jayarathne, R. Weerasooriya, C. Udumalagala Gamage, B. Senevirathne, A.G. Unil Perera, R.D. Jayasinghe. Correlation Between Serum Heavy Metals and the Risk of Oral Cancer and Premalignant Lesion development. Proceedings of Peradeniya University International Research Sessions 2024, Sri Lanka, Vol. 25, 29th & 30th September 2024.
  6. R. Rathiverni, B.R. Fernando, R. M. S. K. Karunarathne, K. Senevirathna, P.M.P.A. Bandara, and R.D. Jayasinghe. Aflatoxins contamination in commercially available areca nut and commercially prepared areca nut products in Sri Lanka. Proceedings of Peradeniya University International Research Sessions 2024, Sri Lanka, Vol. 25, 29th & 30th September 2024.
  7. Y. A. Jayasinghe, S. M. Jayawickrama, K. Senevirathna, R. M. Jayasinghe, R. D. Jayasinghe (2023) Evaluation of Social Media Platforms in Promoting Oral Health Among Sri Lankan Adults: A Survey Based Study, Proceedings of Peradeniya University International Research Sessions 2023, Sri Lanka, Vol. 24, 20th & 21st September 2023.
  8. Y. Jayasinghe, R. Pradeep, S. Jayawickrama, K. Senevirathna, H. Dissanayake, V. Yatawatte, P. Peiris, N. Jayawardena, N. Kuhnert, L. Jayasinghe, R. Jayasinghe (2023) A Comparative Analysis of Four Major Alkaloids in Areca catechu (Areca nut) Varieties Based on Different Preparation Methods in Sri Lanka. Proceedings of Peradeniya University International Research Sessions 2023, Sri Lanka, Vol. 24, 20th & 21st September 2023.
  9. Y.A Jayasinghe, R. Yaddehige, S.M Jayawickrama, K. Senevirathna, B.S.M.S. Siriwardena, R.D Jayasinghe (2023) Preliminary Study on Association between Histopathological and Clinical Characteristics of Oral Leukoplakia, Proceedings of Peradeniya University International Research Sessions 2023, Sri Lanka, Vol. 24, 20th & 21st September 2023.
  10. Pathirage PDMKC, Piyarathne N.S, Senevirathna D.G.P.K, Pradeep R.G.G.R, Jayasinghe, R.D. (2023). A QUANTITATIVE EVALUATION OF THE ASSOCIATIONS BETWEEN TOBACCO USAGE AND C. albicans GROWTH IN PATIENTS WITH ORAL SUBMUCOUS FIBROSIS. The Kandy Society of Medicine, Annual Academic Sessions, 2023 (Abstract Book).
  11. Hettiarachchi T.G.N, Piyarathne, N.S, Pradeep, R.G.G.R, Senevirathna, D.G.P.K, Senanayaka M.R.D.M, Jayathilaka J.A.M.S, Jayasinghe L, Jayasinghe R.D (2023). INVESTIGATION OF THE CHEMICAL COMPOUNDS CONTRIBUTING TO THE ANTIFUNGAL ACTIVITY OF DIFFERENT LOCAL VARIETIES OF Areca catechu EXTRACTS ON THE GROWTH OF Candida albicans. The Kandy Society of Medicine, Annual Academic Sessions, 2023 (Abstract Book).
  12. K. Senevirathna, N.U. Jayawardana, R.W. Pallegama, R.D. Jayasinghe, B. Seneviratne, H. Ghimire, M.K. Dayananda, A.G.U. Perera (2022). Infrared spectroscopic analysis based spectral biomarkers for Oral Cancer Screening: a preliminary analysis, Dental Students’ Research Symposium STURESY 2022.
  13. Senevirathna K, Hettiarachchi K, Warnakulasuriya S, Jayasinghe R (2022). TIKTOK – POTENTIAL IMPACT ON THE USE OF SMOKELESS TOBACCO AND BETEL QUID BY YOUNG PEOPLE. The Kandy Society of Medicine, Annual Academic Sessions, 2022 (Abstract Book).
  14. Senevirathna D.G.P.K, Ranaweera L.T, Sooriyapathirana S.D.S.S (2019). Assessment of morphological diversity and genetic diversity of JAMBU in Kandy district, Sri Lanka. Faculty research Congress, Faculty of science, University of Peradeniya, Peradeniya (Abstract Book).

Teaching

  1. Cell Biochemistry